Short-term, high-dose hydroxychloroquine corneal toxicity
نویسندگان
چکیده
منابع مشابه
Retinal toxicity in long term hydroxychloroquine treatment.
OBJECTIVE To report clinical experience from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) who were receiving recommended doses of hydroxychloroquine for more than six years, and were monitored for evidence of hydroxychloroquine related retinopathy every six months. METHODS A prospective (and continuing) evaluation was made of the potential retinal toxicity of...
متن کاملOcular toxicity of hydroxychloroquine.
OBJECTIVES To review the types, incidence, pathogenesis, risk factors, and clinical characteristics of hydroxychloroquine ocular toxicity and current views about its screening and management. DATA SOURCES Literature search of Medline up to May 2005. STUDY SELECTION Key words for the literature search were 'hydroxychloroquine', 'chloroquine', 'ocular', 'toxicity', 'retinopathy', and 'screeni...
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introduction : methotrexate (mtx) is an anti folate drug that used in malignant and non malignant patients. the usage of high dose methotrexate was limited to patients with: osteogenic sarcoma, ewing sarcoma and lymphoma. the aim this study was to determine the toxicity or side effects of very high dose methotrexate (8-10 gr/m 2 /cycle). this study is the first study in iranian patients and one...
متن کاملComparison of screening procedures in hydroxychloroquine toxicity.
OBJECTIVES To compare different screening procedures for hydroxychloroquine sulfate (Plaquenil) toxicity at different stages of damage. METHODS Ten patients were studied using 10-2 automated fields, multifocal electroretinography, spectral domain optical coherence tomography (SD-OCT), and fundus autofluorescence. RESULTS All 10 patients used hydroxychloroquine for more than 6 years, and tho...
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Cells degrade proteins either by proteasomes that clinically are targeted by for example bortezomib or carfilzomib, or by formation of autophagosomes and lysosomal degradation that can be inhibited by hydroxychloroquine (HCQ). Multiple myeloma is unique among cancers because proteasomal inhibition has good clinical effects. However, some multiple myeloma patients display intrinsic resistance to...
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ژورنال
عنوان ژورنال: American Journal of Ophthalmology Case Reports
سال: 2020
ISSN: 2451-9936
DOI: 10.1016/j.ajoc.2020.100713